Polysaccharide Antibody Deficiency: Specific or General?
نویسندگان
چکیده
منابع مشابه
Specific polysaccharide antibody deficiency in chromosome 18p deletion syndrome and immunoglobulin A deficiency.
Immunoglobulin (Ig) A deficiency has long been recognized in patients with chromosome 18 abnormalities. We present the case of a young girl in whom a chromosome 18p deletion syndrome (46,XX,del[18][p11.1]) was associated not only with IgA deficiency, but also with an inability to make antibody to the unconjugated pneumococcal polysaccharide vaccine, Pneumovax II, indicating a concomitant specif...
متن کاملLaboratory diagnosis of specific antibody deficiency to pneumococcal capsular polysaccharide antigens.
BACKGROUND Measurement of postimmunization antibody response to pneumococcal capsular polysaccharide (caps-PS) is the standard method to identify deficiency of antipolysaccharide antibody production. However, no standardized criteria have been defined for classification of patients into responders or nonresponders to caps-PS. METHODS We vaccinated 37 healthy children and 39 healthy adults wit...
متن کاملClinical and laboratory characteristics of 75 patients with specific polysaccharide antibody deficiency syndrome.
BACKGROUND There are limited studies of large cohorts of patients with specific polysaccharide antibody deficiency (SPAD) syndrome. OBJECTIVE To study the clinical and laboratory characteristics of patients with specific polysaccharide antibody deficiency syndrome. METHODS We retrospectively studied 75 patients with total IgG levels of at least 500 mg/dL and fewer than 9 of 12 responses to ...
متن کاملThe Anamnestic Antibody Response to Type Iii Specific Pneumococcal Polysaccharide
Rabbits immunized with killed type III pneumococci respond to anamnestic challenge by type specific polysaccharide (S III) with the synthesis of anti-S III antibody if a long interval is allowed to elapse between primary and secondary immunization. A study of the anti-S III antibody produced early and late in the immune response revealed no change in molecular class, banding pattern of dissocia...
متن کاملspecific antibody deficiency in children suffering recurrent infections
specific antibody deficiency lias been recognized as an immunodeficiency. in order to investigate an antipolysaccliaride antibody defect as a cause of rcccttrent infections, 30 children were studied. patients who had been identified to have a major immunodeficiency or structural abnormality or a disease known to cause infection were excluded. tliirty patints, aged i to 13.8 years (mean age, 5.8...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2017
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/cix863